J-BHI 2022: Learning Two-Stream CNN for Multi-Modal Age-related Macular Degeneration Categorization

Our work on multi-modal AMD categorization has been published online as a regular paper in IEEE Journal of Biomedical and Health Informatics (Impact factor: 5.772). Source code is available at https://github.com/li-xirong/mmc-amd.
Proposed end-to-end solution for multi-modal AMD categorization
Weisen Wang, Xirong Li, Zhiyan Xu, Weihong Yu, Jianchun Zhao, Dayong Ding, Youxin Chen: Learning Two-Stream CNN for Multi-Modal Age-related Macular Degeneration Categorization. In: IEEE Journal of Biomedical and Health Informatics (J-BHI), 2022.

MICCAI 2019: Two-Stream CNN with Loose Pair Training for Multi-modal AMD Categorization

Our MICCAI’19 paper on multi-modal age-related macular degeneration (AMD) categorization is online.

This paper studies automated categorization of age-related macular degeneration (AMD) given a multi-modal input, which consists of a color fundus image and an optical coherence tomography (OCT) image from a specific eye. Previous work uses a traditional method, comprised of feature extraction and classifier training that cannot be optimized jointly. By contrast, we propose a two-stream convolutional neural network (CNN) that is end-to-end. The CNN’s fusion layer is tailored to the need of fusing information from the fundus and OCT streams. For generating more multi-modal training instances, we introduce Loose Pair training, where a fundus image and an OCT image are paired based on class labels rather than eyes. Moreover, for a visual interpretation of how the individual modalities make contributions, we extend the class activation mapping technique to the multi-modal scenario. Experiments on a real-world dataset collected from an outpatient clinic justify the viability of our proposal for multi-modal AMD categorization.

Weisen Wang, Zhiyan Xu, Weihong Yu, Jianchun Zhao, Jingyuan Yang, Feng He, Zhikun Yang, Di Chen, Dayong Ding, Youxin Chen, Xirong Li: Two-Stream CNN with Loose Pair Training for Multi-modal AMD Categorization. In: International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), 2019, (early accept).